Structure of PDB 2ynb Chain B

Receptor sequence
>2ynbB (length=302) Species: 694007 (Tylonycteris bat coronavirus HKU4) [Search protein sequence]
SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLT
DPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPS
TPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGS
VGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTD
KYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQS
IDMLAHRTGVSVEQMLAAIQSLHAGFQGKTILGQSTLEDEFTPDDVNMQV
MG
3D structure
PDB2ynb Inhibitor for the Main Protease of Coronavirus Hku4
ChainB
Resolution1.96 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H41 G146 C148
Catalytic site (residue number reindexed from 1) H41 G146 C148
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G85 B M25 T26 H41 L49 F143 G146 C148 H166 Q167 M168 E169 L170 D190 K191 Q192 T193 Q195 M25 T26 H41 L49 F143 G146 C148 H166 Q167 M168 E169 L170 D190 K191 Q192 T193 Q195
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2ynb, PDBe:2ynb, PDBj:2ynb
PDBsum2ynb
PubMed
UniProtP0C6T4|R1A_BCHK4 Replicase polyprotein 1a (Gene Name=1a)

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