Structure of PDB 2yjd Chain B

Receptor sequence
>2yjdB (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISW
AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVL
DRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSSSR
KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGME
HLLNMKCKNVVPVYDLLLEMLNA
3D structure
PDB2yjd Design and Structure of Stapled Peptides Binding to Estrogen Receptors.
ChainB
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I310 K314 L324 V328 L490 E493 I48 K52 L62 V66 L216 E219
BS02 YJD B E305 L339 L343 F356 I373 I376 F377 L380 L476 E43 L77 L81 F94 I111 I114 F115 L118 L202
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2yjd, PDBe:2yjd, PDBj:2yjd
PDBsum2yjd
PubMed21612236
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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