Structure of PDB 2yev Chain B

Receptor sequence

>2yevB (length=319) Species: 300852 (Thermus thermophilus HB8)

AHRVAITHPGGSFNQEVAFLFPWVYFFSFLIFLVVAGSLAYVTWKFRARP
EDQEEPPQIHGNDRLEVVWTLIPLAIVFVLFGLTAKALIQVNRPIPGAMK
VEVTGYQFWWDFHYPELGLRNSNELVLPAGVPVELEITSKDVIHSFWVPG
LAGKRDAIPGQTTRISFEPKEPGLYYGFCAELCGASHARMLFRVVVLPKE
EFDRFVEAAKASPAPVADERGQQVFQQNCAACHGVARSMPPAVIGPELGL
WGNRTSLGAGIVENTPENLKAWIRDPAGMKPGVKMPGFPQLSEEDLDALV
RYLEGLKVEGFDFGALPKF

3D structure

• PDB: 2yev Structural Insights Into Electron Transfer in Caa3-Type Cytochrome Oxidases.
• Chain: B
• Resolution: 2.36 Å

Enzymatic activity

• Enzyme Commision number: 7.1.1.9: cytochrome-c oxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HAS	B	S46 I49 L98	S28 I31 L80
BS02	CUA	B	H162 C197 E199 C201 H205 M208	H144 C179 E181 C183 H187 M190
BS03	HEC	B	F126 W127 N141 N246 C247 C250 H251 P264 W269 R272 L275 G276 W290 I291 K298 V301 M303 F306	F108 W109 N123 N228 C229 C232 H233 P246 W251 R254 L257 G258 W272 I273 K280 V283 M285 F288

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0005507 copper ion binding
• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0022900 electron transport chain
• GO:0042773 ATP synthesis coupled electron transport
• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:2yev, PDBe:2yev, PDBj:2yev
• PDBsum: 2yev
• PubMed: 22763450
• UniProt: Q5SLI2