Structure of PDB 2ycb Chain B

Receptor sequence

>2ycbB (length=635) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H)

VSEMLEEIKRTIMQRLPERVQVAKVEFEGPEVVIYTKNPEIITENGNLIR
DIAKDIRKRIIIRSDRSVLMDPEKAIRKIHEIVPEEAKITNISFDDVTCE
VIIEARKPGLVIGKYGSTSREIVKNTGWAPKILRTPPISSEIIERIRRTL
RKNSKERKKILQQLGNRIHQKPKYDNDWARLTAMGGFREVGRSCLYLQTP
NSRVLLDCGVNVAGGDDKNSYPYLNVPEFTLDSLDAVIITHAHLDHSGFL
PYLYHYGYDGPVYCTAPTRDLMTLLQLDHIDIAHREDEPLPFNVKHVKKS
VKHTITLDYGEVTDIAPDIRLTLHNAGHILGSAMAHLHIGDGQHNMVYTG
DFKYEQSRLLEAAANRFPRIETLVMESTYGGHEDVQPSRNRAEKELVKTI
YSTLRRGGKILIPVFAVGRAQELMIVLEEYIRTGIIDEVPVYIDGMIWEA
NAIHTARPEYLSKDLRDQIFHMGHNPFISDIFHKVNGMDERREIVEGEPS
IILSTSGMLTGGNSLEYFKWLCEDPDNSLVFVGYQAEGSLGRRIQKGWKE
IPLKDEDDKMRVYNVRMNIKTIEGFSGHSDRRQLMEYVKRISPKPEKILL
CHGDNYKTLDLASSIYRTYRIETKTPLNLETVRIQ

3D structure

• PDB: 2ycb Structure and Activity of a Novel Archaeal Beta-Casp Protein with N-Terminal Kh Domains.
• Chain: B
• Resolution: 3.1 Å

Enzymatic activity

• Enzyme Commision number: 3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	B	D246 H247 D352 H603	D245 H246 D351 H602
BS02	ZN	B	H242 H244 H329 D352	H241 H243 H328 D351

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003677 DNA binding
• GO:0003723 RNA binding
• GO:0004519 endonuclease activity
• GO:0004521 RNA endonuclease activity
• GO:0004527 exonuclease activity
• GO:0004540 RNA nuclease activity
• GO:0008270 zinc ion binding
• GO:0042802 identical protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006353 DNA-templated transcription termination

External links

• PDB: RCSB:2ycb, PDBe:2ycb, PDBj:2ycb
• PDBsum: 2ycb
• PubMed: 21565697
• UniProt: O27271|FTTA_METTH Transcription termination factor FttA (Gene Name=fttA)