Structure of PDB 2y2x Chain B

Receptor sequence

>2y2xB (length=378) Species: 208964 (Pseudomonas aeruginosa PAO1)

GFLEDAKTDLVLRNYYFNRDFRDLVDEWAQGFILKFSSGYTPGTVGVGLD
AIGLFGVKLNSGTSNELLPLHDDGRAADNYGRVGVAAKLRVSASELKIGE
MLPDIPLLRYDDGRLLPQTFRGFAVVSRELPGLALQAGRFDAVSLRNSAD
MQDLSAWSAPTQKSDGFNYAGAEYRFNRERTQLGLWHGQLEDVYRQSYAN
LLHKQRVGDWTLGANLGLFVDRDDGAARAGEIDSHTVYGLFSAGIGLHTF
YLGLQKVGGDSGWQSVYGSSGRSMGNDMFNGNFTNADERSWQVRYDYDFV
GLGWPGLIGMVRYGHGSNATTKAGSGGKEWERDVELGYTVQSGPLARLNV
RLNHASNRRSFNSDFDQTRLVVSYPLSW

3D structure

• PDB: 2y2x Pseudomonas Aeruginosa Opdk with Vanillate
• Chain: B
• Resolution: 1.65 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	C8E	B	G62 L63	G53 L54
BS02	C8E	B	Y122 D124	Y110 D112
BS03	C8E	B	Y325 W342 R344	Y313 W330 R332
BS04	C8E	B	H260 Y307	H248 Y295
BS05	C8E	B	R94 D162 M163	R82 D150 M151
BS06	C8E	B	H215 L224 G225 F253	H203 L212 G213 F241
BS07	VNL	B	K44 F45 D59 A60 I61 M113	K35 F36 D50 A51 I52 M101
BS08	VNL	B	H327 K340 E341 W342 R370 R371	H315 K328 E329 W330 R358 R359

Gene Ontology

Molecular Function

• GO:0015288 porin activity

Biological Process

• GO:0055085 transmembrane transport

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:2y2x, PDBe:2y2x, PDBj:2y2x
• PDBsum: 2y2x
• UniProt: Q9HUR5