Structure of PDB 2y04 Chain B

Receptor sequence
>2y04B (length=298) Species: 9103 (Meleagris gallopavo) [Search protein sequence]
AELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITS
LACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETL
CVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWW
RDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYR
EAKEQIRKIDRASKRKTSRVMLMREHKALKTLGIIMGVFTLCWLPFFLVN
IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYCRSPDFRKAFKRLLA
3D structure
PDB2y04 The Structural Basis for Agonist and Partial Agonist Action on a Beta1-Adrenergic Receptor
ChainB
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y01 B R205 A206 A210 R173 A174 A178
BS02 2CV B L152 R157 L120 R125
BS03 Y01 B E130 R157 V160 T164 E98 R125 V128 T132
BS04 Y01 B C85 R155 W166 C53 R123 W134
BS05 2CV B W181 E185 W149 E153
BS06 68H B D121 V122 S211 F306 F307 N329 D89 V90 S179 F246 F247 N269
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004935 adrenergic receptor activity
GO:0004940 beta1-adrenergic receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0045823 positive regulation of heart contraction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2y04, PDBe:2y04, PDBj:2y04
PDBsum2y04
PubMed21228877
UniProtP07700|ADRB1_MELGA Beta-1 adrenergic receptor (Gene Name=ADRB1)

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