Structure of PDB 2xzs Chain B

Receptor sequence
>2xzsB (length=293) Species: 9606 (Homo sapiens) [Search protein sequence]
FRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRGVSRE
DIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKE
SLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKI
IDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYI
LLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKD
PKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAAR
3D structure
PDB2xzs Death-Associated Protein Kinase Activity is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D139 K141 E143 N144 D161 T180
Catalytic site (residue number reindexed from 1) D130 K132 E134 N135 D152 T171
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B N144 D161 N135 D152
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2xzs, PDBe:2xzs, PDBj:2xzs
PDBsum2xzs
PubMed27133022
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

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