Structure of PDB 2xyp Chain B

Receptor sequence
>2xypB (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
3D structure
PDB2xyp In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
ChainB
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XVE B Y204 F256 Y20 F72
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2xyp, PDBe:2xyp, PDBj:2xyp
PDBsum2xyp
PubMed21821879
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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