Structure of PDB 2xvn Chain B

Receptor sequence
>2xvnB (length=309) [Search protein sequence]
SNLAIYWGQGPNQLRLSHFCQETSLDIINIGFINYFPDMSPGHWPGSNFG
NQCDGSVYVTNDGVVTKLLSGCHQIMEDIPICQAAGKKVLLSIGGAYPPD
QSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVVDGFDFDIEHNGG
FGYATMVNTFRQYFNQVPERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIW
IQYYNTAACSAKSFIDTSLGTFNFDAWVTVLKASASKDAKLYVGLPASET
AANQGYYLTPDEVESLVSTYMDRYPDTFGGIMLWEATASENNQIDGAPYA
DHMKDILLH
3D structure
PDB2xvn Natural Product-Guided Discovery of a Fungal Chitinase Inhibitor.
ChainB
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.14: chitinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KLS B Y34 A124 D172 E174 Q230 Y232 W312 Y6 A96 D144 E146 Q202 Y204 W284 MOAD: ic50=112uM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2xvn, PDBe:2xvn, PDBj:2xvn
PDBsum2xvn
PubMed21168763
UniProtQ873Y0|CHIA1_ASPFM Endochitinase A1 (Gene Name=chiA1)

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