Structure of PDB 2x6v Chain B

Receptor sequence
>2x6vB (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
EGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYI
LLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQ
LVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADTAFCTHVFPETA
FIAVTSYQNHKITQLKIENNPF
3D structure
PDB2x6v Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B E60 S86 E9 S35
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2x6v, PDBe:2x6v, PDBj:2x6v
PDBsum2x6v
PubMed20450920
UniProtQ99593|TBX5_HUMAN T-box transcription factor TBX5 (Gene Name=TBX5)

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