Structure of PDB 2x6s Chain B

Receptor sequence
>2x6sB (length=184) Species: 11963 (Human spumaretrovirus) [Search protein sequence]
PQKPFDKFFMDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTKAPSTSATV
KSLNVLTSIAIPRVIHSDQGAAFTSSTFAEWAKERGIHLEFSTPYHPSKV
ERKNSDMKRLLTKLLVGRPTKWYDLLPVVQLAMNNTYSPVLKYTPHQLLF
GIDSNTPFANQDTLDLTREEELSLLQEIRTSLYH
3D structure
PDB2x6s Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase
ChainB
Resolution2.29 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG B D128 D185 D11 D68
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2x6s, PDBe:2x6s, PDBj:2x6s
PDBsum2x6s
PubMed20693659
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

[Back to BioLiP]