Structure of PDB 2wyv Chain B

Receptor sequence
>2wyvB (length=247) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MLTVDLSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEA
EKLAEALGGALLFRADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPRE
AMEGRYIDTRRQDWLLALEVSAYSLVAVARRAEPLLREGGGIVTLTYYAS
EKVVPKYNVMAIAKAALEASVRYLAYELGPKGVRVNAISAGPVRTYDRVA
QTAPLRRNITQEEVGNLGLFLLSPLASGITGEVVYVDAGYHIMGMEL
3D structure
PDB2wyv High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan.
ChainB
Resolution1.86 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S21 Y147 Y157 M160 K164
Catalytic site (residue number reindexed from 1) S21 Y147 Y157 M160 K164
Enzyme Commision number 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G15 T17 S21 L22 Q42 V67 I94 A95 L145 T146 K164 A190 G15 T17 S21 L22 Q42 V67 I94 A95 L145 T146 K164 A190
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006633 fatty acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2wyv, PDBe:2wyv, PDBj:2wyv
PDBsum2wyv
PubMed23027736
UniProtQ5SLI9

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