Structure of PDB 2wtl Chain B

Receptor sequence
>2wtlB (length=161) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
QGDPDVLRLLNEQLTSELTAINQYFLHSKMQDNWGFTELAAHTRAESFDE
MRHAEEITDRILLLDGLPNYQRIGSLRIGQTLREQFEADLAIEYDVLNRL
KPGIVMCREKQDTTSAVLLEKIVADEEEHIDYLETQLELMDKLGEELYSA
QCVSRPPTSAW
3D structure
PDB2wtl Crystal Structure of Bfra from Mycobacterium Tuberculosis:Incorporation of Selenomethionine Results in Cleavage and Demetallation of Haem
ChainB
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE B E18 E51 E127 E17 E50 E126
BS02 FE B E51 E94 E127 H130 E50 E93 E126 H129
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0005506 iron ion binding
GO:0008199 ferric iron binding
GO:0015093 ferrous iron transmembrane transporter activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
GO:0010039 response to iron ion
GO:0034755 iron ion transmembrane transport
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wtl, PDBe:2wtl, PDBj:2wtl
PDBsum2wtl
PubMed19946376
UniProtP9WPQ9|BFR_MYCTU Bacterioferritin BfrA (Gene Name=bfr)

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