Structure of PDB 2whd Chain B

Receptor sequence
>2whdB (length=319) Species: 4513 (Hordeum vulgare) [Search protein sequence]
AAAPLRTRVCIIGSGPAAHTAAIYAARAELKPVLFEGWMANDIAAGGQLT
TTTDVENFPGFPTGIMGIDLMDNCRAQSVRFGTNILSETVTEVDFSARPF
RVTSDSTTVLADTVVVATGAVARRLYFSGSDTYWNRGISACAVCDGAAPI
FRNKPIAVIGGGDSAMEEGNFLTKYGSQVYIIHRRNTFRASKIMQARALS
NPKIQVVWDSEVVEAYGGAGGGPLAGVKVKNLVTGEVSDLQVSGLFFAIG
HEPATKFLNGQLELHADGYVATKPGSTHTSVEGVFAAGDVQDKKYRQAIT
AAGSGCMAALDAEHYLQEV
3D structure
PDB2whd Structure of Hordeum Vulgare Nadph-Dependent Thioredoxin Reductase 2. Unwinding the Reaction Mechanism.
ChainB
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C145 C148 D149
Catalytic site (residue number reindexed from 1) C141 C144 D145
Enzyme Commision number 1.8.1.9: thioredoxin-disulfide reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G17 S18 G19 P20 A21 G41 A44 G51 Q52 L53 T56 N61 T93 V94 T122 G123 C148 G292 D293 R300 Q301 A302 G13 S14 G15 P16 A17 G37 A40 G47 Q48 L49 T52 N57 T89 V90 T118 G119 C144 G288 D289 R296 Q297 A298
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004791 thioredoxin-disulfide reductase (NADPH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0019430 removal of superoxide radicals
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2whd, PDBe:2whd, PDBj:2whd
PDBsum2whd
PubMed19690371
UniProtA9LN30

[Back to BioLiP]