Structure of PDB 2wfx Chain B

Receptor sequence
>2wfxB (length=417) Species: 9606 (Homo sapiens) [Search protein sequence]
NCFCIQEVVSGLRQPVGALHSGDGSQRLFILEKEGYVKILTPEGEIFKEP
YLDIHKLVQSGIKDERGLLSLAFHPNYKKNGKLYVSYTTNDHILRVVEYT
VSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFGPDGFLYIILGDGMIT
LDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQPPEVF
AHGLHDPGRCAVDRHPTDININLTILCSDSNRSSARILQIIKGKDYESEP
SLLEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTK
QWQEKPLCLHILGFGEDELGEVYILSSTHNGKLYKIVDPKRPLMPEECRA
TVQPAQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRTAKCEPACRHG
GVCVRPNKCLCYLGPQC
3D structure
PDB2wfx Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B D383 C666 D158 C417
External links
PDB RCSB:2wfx, PDBe:2wfx, PDBj:2wfx
PDBsum2wfx
PubMed19561611
UniProtQ96QV1|HHIP_HUMAN Hedgehog-interacting protein (Gene Name=HHIP)

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