Structure of PDB 2wbi Chain B

Receptor sequence
>2wbiB (length=398) Species: 9606 (Homo sapiens) [Search protein sequence]
VQTRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDK
LKEMAKVEGLWNLFLPAVSGLSHVDYALIAEETGKCFFAPDVFNCQAPDT
GNMEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSI
QRDEDSYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSQHSMILVPMNTPG
VKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGEGRGFEISQGRL
GPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAESR
IAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQV
CGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRL
3D structure
PDB2wbi Crystal Structure of Human Acyl-Coa Dehydrogenase 11
ChainB
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) M154 T155 G279 D402 T414
Catalytic site (residue number reindexed from 1) M133 T134 G253 D376 T388
Enzyme Commision number 1.3.8.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B R305 F308 H315 Q375 V376 G378 G379 R279 F282 H289 Q349 V350 G352 G353
BS02 FAD B M154 T155 A160 S161 S162 W186 S188 H246 V397 L400 P404 E406 M133 T134 A139 S140 S141 W165 S167 H220 V371 L374 P378 E380
Gene Ontology
Molecular Function
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding

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Molecular Function
External links
PDB RCSB:2wbi, PDBe:2wbi, PDBj:2wbi
PDBsum2wbi
PubMed
UniProtQ709F0|ACD11_HUMAN Acyl-CoA dehydrogenase family member 11 (Gene Name=ACAD11)

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