Structure of PDB 2w68 Chain B

Receptor sequence
>2w68B (length=193) Species: 666 (Vibrio cholerae) [Search protein sequence]
MALFDYNATGDTEFDSPAKQGWMQDNTNNGSGVLTNADGMPAWLVQGIGG
RAQWTYSLSTNQHAQASSFGWRMTTEMKVLSGGMITNYYANGTQRVLPII
SLDSSGNLVVEFEGQTGRTVLATGTAATEYHKFELVFLPGSNPSASFYFD
GKLIRDNIQPTASKQNMIVWGNGSSNTDGVAAYRDIKFEIQGD
3D structure
PDB2w68 Enhancing the Receptor Affinity of the Sialic Acid-Binding Domain of Vibrio Cholerae Sialidase Through Multivalency
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA B R74 R118 Q188 G196 S197 S198 R51 R95 Q165 G173 S174 S175
Gene Ontology
Molecular Function
GO:0033691 sialic acid binding

View graph for
Molecular Function
External links
PDB RCSB:2w68, PDBe:2w68, PDBj:2w68
PDBsum2w68
PubMed19124471
UniProtP0C6E9|NANH_VIBCH Sialidase (Gene Name=nanH)

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