Structure of PDB 2w40 Chain B

Receptor sequence
>2w40B (length=503) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
GSMNVILSIDQSTQSTKVFFYDEELNIVHSNNLNHEQKCLKPGWYEHDPI
EIMTNLYNLMNEGIKVLKDKYTSVIIKCIGITNQRETVIIWDRITGKPLY
NAIVWLDTRVEELVTEFSAKYNNNDIQKKTGTYFNTYFSAFKILWLIQNN
PEIKQKIDDGTAVIGNINTWLIFNLTKGNCYTDVTNASRTLLMDINTLQW
DEKMCKIFNITNMSVLPEIKSNCSNFGLVKSEHVPDYLNIPITGCIGDQQ
SACIGQAIFDEGEAKCTYGTGVFLLINTGEKVVYSTCGLITTICYKFNDN
DKPKYALEGSIGTAGSGVSWLLKNKLIDDPSEASDIMEKCENTTGVIFVP
AFSGLYAPRWRSDARASIYGMTFNTERSHIVRALLEGIAFQLNEIVDSLT
SDMGIEMLHVLRCDGGMTKNKPFMQFNSDIINTKIEVSKYKEVTSLGAAV
LAGLEVKIWDSLDSVKSLLRRSDAVFHSKMDDKKRKKKTSEWNKAVERTL
IQL
3D structure
PDB2w40 Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages.
ChainB
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.30: glycerol kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL B R83 E84 W103 Y135 D246 F271 R85 E86 W105 Y137 D248 F273
BS02 GOL B C221 N296 D297 E453 C223 N298 D299 E455
Gene Ontology
Molecular Function
GO:0004370 glycerol kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006071 glycerol metabolic process
GO:0006072 glycerol-3-phosphate metabolic process
GO:0006641 triglyceride metabolic process
GO:0016310 phosphorylation
GO:0019563 glycerol catabolic process
GO:0046167 glycerol-3-phosphate biosynthetic process
Cellular Component
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2w40, PDBe:2w40, PDBj:2w40
PDBsum2w40
PubMed19040641
UniProtQ8IDI4

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