Structure of PDB 2w3o Chain B

Receptor sequence
>2w3oB (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
GRLWLESPPGEAPPIFLPSDGQALVLGRGPLTQVTDRKCSRTQVELVADP
ETRTVAVKQLGVNPSTTGTQELKPGLEGSLGVGDTLYLVNGEHPLTLRWE
E
3D structure
PDB2w3o Specific Recognition of a Multiply Phosphorylated Motif in the DNA Repair Scaffold Xrcc1 by the Fha Domain of Human Pnk.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.78: polynucleotide 5'-hydroxyl-kinase.
3.1.3.32: polynucleotide 3'-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R35 G36 P37 Q40 V41 R44 K45 S47 R48 V69 N70 N97 R28 G29 P30 Q33 V34 R37 K38 S40 R41 V62 N63 N90
External links
PDB RCSB:2w3o, PDBe:2w3o, PDBj:2w3o
PDBsum2w3o
PubMed19155274
UniProtQ96T60|PNKP_HUMAN Bifunctional polynucleotide phosphatase/kinase (Gene Name=PNKP)

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