Structure of PDB 2w3h Chain B

Receptor sequence
>2w3hB (length=144) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRI
GHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVR
VRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARL
3D structure
PDB2w3h Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM B G84 F98 Y100 I103 I111 H113 L114 P115 K116 G117 L118 G119 S142 I143 F145 P146 H149 M152 T173 G23 F37 Y39 I42 I50 H52 L53 P54 K55 G56 L57 G58 S81 I82 F84 P85 H88 M91 T112
External links
PDB RCSB:2w3h, PDBe:2w3h, PDBj:2w3h
PDBsum2w3h
PubMed19276084
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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