Structure of PDB 2w3g Chain B

Receptor sequence
>2w3gB (length=146) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRI
GHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVR
VRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQ
3D structure
PDB2w3g Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.
ChainB
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM B F98 Y100 I103 H113 P115 K116 G117 L118 S142 I143 G144 F145 P146 H149 M152 F155 Y171 F37 Y39 I42 H52 P54 K55 G56 L57 S81 I82 G83 F84 P85 H88 M91 F94 Y110
External links
PDB RCSB:2w3g, PDBe:2w3g, PDBj:2w3g
PDBsum2w3g
PubMed19276084
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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