Structure of PDB 2w3f Chain B

Receptor sequence
>2w3fB (length=144) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
DLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIG
HLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRV
RDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLY
3D structure
PDB2w3f Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM B G84 I103 I111 H113 L114 P115 K116 G117 L118 S142 I143 G144 F145 P146 H149 M152 F155 T173 G22 I41 I49 H51 L52 P53 K54 G55 L56 S80 I81 G82 F83 P84 H87 M90 F93 T111
External links
PDB RCSB:2w3f, PDBe:2w3f, PDBj:2w3f
PDBsum2w3f
PubMed19276084
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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