Structure of PDB 2w35 Chain B

Receptor sequence
>2w35B (length=223) Species: 2336 (Thermotoga maritima) [Search protein sequence]
MDYRQLHRWDLPPEEAIKVQNELRKKIKLTPYEGEPEYVAGVDLSFPGKE
EGLAVIVVLEYPSFKILEVVSERGEITFPYIPGLLAFREGPLFLKAWEKL
RTKPDVVVFDGQGLAHPRKLGIASHMGLFIEIPTIGVAKSRLYGTFKMPE
DKRCSWSYLYDGEEIIGCVIRTKEGSAPIFVSPGHLMDVESSKRLIKAFT
LPGRRIPEPTRLAHIYTQRLKKG
3D structure
PDB2w35 Structures of Endonuclease V with DNA Reveal Initiation of Deaminated Adenine Repair.
ChainB
Resolution2.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.21.7: deoxyribonuclease V.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K222 G223 K222 G223
BS02 dna B Y80 P82 G83 L85 D110 Q112 H116 I122 A138 K139 S140 R141 L142 Y80 P82 G83 L85 D110 Q112 H116 I122 A138 K139 S140 R141 L142
BS03 dna B S45 F46 K221 S45 F46 K221
BS04 MG B D43 D110 D43 D110
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003727 single-stranded RNA binding
GO:0004519 endonuclease activity
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters
GO:0043737 deoxyribonuclease V activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2w35, PDBe:2w35, PDBj:2w35
PDBsum2w35
PubMed19136958
UniProtQ9X2H9|NFI_THEMA Endonuclease V (Gene Name=nfi)

[Back to BioLiP]