Structure of PDB 2vv1 Chain B

Receptor sequence
>2vv1B (length=239) Species: 9606 (Homo sapiens) [Search protein sequence]
SDLRALAKHLYDSYIKSFPLTKAKARAILTGKDKSPFVIYDMNSLMMGEV
AIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIY
TMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNAL
ELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPE
SSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTPLLQEIY
3D structure
PDB2vv1 Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4HD B C285 R288 I326 V339 S342 M364 C58 R61 I99 V112 S115 M137
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2vv1, PDBe:2vv1, PDBj:2vv1
PDBsum2vv1
PubMed19172745
UniProtP37231|PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (Gene Name=PPARG)

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