Structure of PDB 2vv0 Chain B

Receptor sequence
>2vv0B (length=252) Species: 9606 (Homo sapiens) [Search protein sequence]
SADLRALAKHLYDSYIKSFPLTKAKARAILTGKDKSPFVIYDMNSLMMGE
DKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKY
GVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEF
AVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ
LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETHPLLQEIYK
DL
3D structure
PDB2vv0 Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
ChainB
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HXA B C285 R288 I326 L330 I341 S342 M348 C65 R68 I106 L110 I121 S122 M128
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2vv0, PDBe:2vv0, PDBj:2vv0
PDBsum2vv0
PubMed19172745
UniProtP37231|PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (Gene Name=PPARG)

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