Structure of PDB 2vr3 Chain B

Receptor sequence

>2vr3B (length=310) Species: 1280 (Staphylococcus aureus) [Search protein sequence]

TDITNQLTNVTVGIDSGTTVYPHQAGYVKLNYGFSVPNSAVKGDTFKITV
PKELNLNGVTSTAKVPPIMAGDQVLANGVIDSDGNVIYTFTDYVNTKCDV
KATLTMPAYIDPENVKKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNLS
IKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKPNTDSNALIDQQ
NTSIKVYKVNAADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFPDDQ
ITTPYIVVVNGHIDPNSKGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNG
SGSGDGIDCP

3D structure

PDB

2vr3 A Structural Model of the Staphylococcus Aureus Clfa-Fibrinogen Interaction Opens New Avenues for the Design of Anti-Staphylococcal Therapeutics.

Chain

Resolution

1.95 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	C541 P542	C309 P310
BS02	peptide	B	H252 Q253 A254 N286 V288 T289 Y338 F375 T383 I384 K389 R506 R519 S520 M521 S522 W523 D524 N525 E526 V527 A528 F529 N530	H23 Q24 A25 N57 V59 T60 Y109 F146 T154 I155 K160 R274 R287 S288 M289 S290 W291 D292 N293 E294 V295 A296 F297 N298

Gene Ontology

	Biological Process
GO:0007155	cell adhesion

	Cellular Component
GO:0005618	cell wall

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:2vr3, PDBe:2vr3, PDBj:2vr3
PDBsum	2vr3
PubMed	19043557
UniProt	Q2G015\|CLFA_STAA8 Clumping factor A (Gene Name=clfA)

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