Structure of PDB 2vn1 Chain B

Receptor sequence
>2vn1B (length=123) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
EFEKVELTADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVF
DSSFDRNVPFKFHLEQGEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEG
CGESIPGNSVLLFEIELLSFREL
3D structure
PDB2vn1 Crystal Structure of the Fk506 Binding Domain of Plasmodium Falciparum Fkbp35 in Complex with Fk506.
ChainB
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y44 F55 D56 I75 Y101 F118
Catalytic site (residue number reindexed from 1) Y39 F50 D51 I70 Y96 F113
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK5 B H43 S57 F59 D60 K90 E119 L128 H38 S52 F54 D55 K85 E114 L123
BS02 FK5 B Y44 D56 R61 F65 E73 V74 W78 Y101 F118 Y39 D51 R56 F60 E68 V69 W73 Y96 F113
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:2vn1, PDBe:2vn1, PDBj:2vn1
PDBsum2vn1
PubMed18465874
UniProtQ8I4V8|FKB35_PLAF7 Peptidyl-prolyl cis-trans isomerase FKBP35 (Gene Name=FKBP35)

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