Structure of PDB 2vdr Chain B

Receptor sequence
>2vdrB (length=455) Species: 9606 (Homo sapiens) [Search protein sequence]
GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCA
PESIEFPVSEARVLEDRPLSDKQVTQVSPQRIALRLRPDDSKNFSIQVRQ
VEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAF
VDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEE
VKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHI
ALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINL
IFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVE
LEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGC
PQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFE
CGVCR
3D structure
PDB2vdr Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B S121 Y122 S123 N215 R216 A218 E220 S115 Y116 S117 N209 R210 A212 E214
BS02 MG B S121 S123 E220 S115 S117 E214
BS03 CA B S123 D126 D127 D251 S117 D120 D121 D245
BS04 CA B D158 N215 D217 P219 E220 D152 N209 D211 P213 E214
External links
PDB RCSB:2vdr, PDBe:2vdr, PDBj:2vdr
PDBsum2vdr
PubMed18710925
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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