Structure of PDB 2v5k Chain B

Receptor sequence
>2v5kB (length=260) Species: 498388 (Escherichia coli C) [Search protein sequence]
TENLYFQGAMENSFKAALKAGRPQIGLWLGLSSSYSAELLAGAGFDWLLI
DGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGTQTLL
VPMVQNADEAREAVRATRYPPAGIRGVGSALARASRWNRIPDYLQKANDQ
MCVLVQIETREAMKNLPQILDVEGVDGVFIGPADLSADMGYAGNPQHPEV
QAAIEQAIVQIRESGKAPGILIANEQLAKRYLELGALFVAVGVDTTLLAR
AAEALAARFG
3D structure
PDB2v5k Structure and Mechanism of Hpch: A Metal Ion Dependent Class II Aldolase from the Homoprotocatechuate Degradation Pathway of Escherichia Coli.
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H45 R70 D84 E149 D175
Catalytic site (residue number reindexed from 1) H54 R79 D93 E158 D184
Enzyme Commision number 4.1.2.52: 4-hydroxy-2-oxoheptanedioate aldolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B F250 G251 F259 G260
BS02 MG B E149 D175 E158 D184
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016832 aldehyde-lyase activity
GO:0043863 4-hydroxy-2-ketopimelate aldolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009056 catabolic process
GO:0010124 phenylacetate catabolic process
Cellular Component
GO:0005737 cytoplasm

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External links
PDB RCSB:2v5k, PDBe:2v5k, PDBj:2v5k
PDBsum2v5k
PubMed17881002
UniProtQ47098|HPCH_ECOLX 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase (Gene Name=hpcH)

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