Structure of PDB 2v1x Chain B

Receptor sequence
>2v1xB (length=527) Species: 9606 (Homo sapiens) [Search protein sequence]
SSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLV
MPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARR
FTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVL
TDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRY
KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSA
NEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKA
DCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHF
DEVWACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPLKL
IDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYA
TISYLKIGPKANLLNNEAHAITMQVTK
3D structure
PDB2v1x Structure of the Human Recq1 Helicase Reveals a Putative Strand-Separation Pin.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B L89 R93 Q96 T115 G116 G118 K119 S120 D379 L27 R31 Q34 T53 G54 G56 K57 S58 D317
BS02 ZN B C453 C471 C475 C478 C391 C406 C410 C413
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:2v1x, PDBe:2v1x, PDBj:2v1x
PDBsum2v1x
PubMed19151156
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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