Structure of PDB 2v0n Chain B

Receptor sequence
>2v0nB (length=454) Species: 190650 (Caulobacter vibrioides CB15) [Search protein sequence]
SARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDIIL
LDVMMPGMDGFTVCRKLKDDPTTRHIPVVLITALDGRGDRIQGLESGASD
FLTKPIDDVMLFARVRSLTRFKLVIDELRQREASGRRMGVIAGAAARLDG
LGGRVLIVDDNERQAQRVAAELGVEHRPVIESDPEKAKISAGGPVDLVIV
NAAAKNFDGLRFTAALRSEERTRQLPVLAMVDPDDRGRMVKALEIGVNDI
LSRPIDPQELSARVKTQIQRKRYTDYLRNNLDHSLELAVTDQLTGLHNRR
YMTGQLDSLVKRATLGGDPVSALLIDIDFFKKINDTFGHDIGDEVLREFA
LRLASNVRAIDLPCRYGGEEFVVIMPDTALADALRIAERIRMHVSGSPFT
VAHGREMLNVTISIGVSATAGEGDTPEALLKRADEGVYQAKASGRNAVVG
KAAH
3D structure
PDB2v0n Structure of Bef3--Modified Response Regulator Pled: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition
ChainB
Resolution2.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.65: diguanylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2E B R313 L316 R312 L315 PDBbind-CN: -logKd/Ki=6.30,Ki=0.5uM
BS02 BEF B D53 V54 M55 T83 A84 K105 D52 V53 M54 T82 A83 K104
BS03 MG B D10 D53 M55 D9 D52 M54
BS04 C2E B R359 D362 D383 I387 R390 R358 D361 D382 I386 R389 PDBbind-CN: -logKd/Ki=6.30,Ki=0.5uM
BS05 C2E B N357 R359 R390 N356 R358 R389 PDBbind-CN: -logKd/Ki=6.30,Ki=0.5uM
BS06 GAV B I328 F330 F331 K332 N335 H340 D344 L347 G369 E370 K442 R446 I327 F329 F330 K331 N334 H339 D343 L346 G368 E369 K441 R445
BS07 MG B D327 I328 E370 D326 I327 E369
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0052621 diguanylate cyclase activity
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0030154 cell differentiation
GO:0043709 cell adhesion involved in single-species biofilm formation
GO:1902201 negative regulation of bacterial-type flagellum-dependent cell motility
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2v0n, PDBe:2v0n, PDBj:2v0n
PDBsum2v0n
PubMed17697997
UniProtB8GZM2|PLED_CAUVN Response regulator PleD (Gene Name=pleD)

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