Structure of PDB 2rlb Chain B

Receptor sequence
>2rlbB (length=152) Species: 9913 (Bos taurus) [Search protein sequence]
EKTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVGQSPDMYSYVFRVC
REAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEY
DNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLA
CS
3D structure
PDB2rlb Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M6D B Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y43 Q64 Y100 D101 N102 H103 R109 E131 R133 Y141
Gene Ontology
Molecular Function
GO:0019904 protein domain specific binding
Biological Process
GO:0006622 protein targeting to lysosome
Cellular Component
GO:0005768 endosome
GO:0005794 Golgi apparatus

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Cellular Component
External links
PDB RCSB:2rlb, PDBe:2rlb, PDBj:2rlb
PDBsum2rlb
PubMed18272523
UniProtP11456|MPRD_BOVIN Cation-dependent mannose-6-phosphate receptor (Gene Name=M6PR)

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