Structure of PDB 2rl9 Chain B

Receptor sequence
>2rl9B (length=151) Species: 9913 (Bos taurus) [Search protein sequence]
KTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCR
EAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYD
NHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLAC
S
3D structure
PDB2rl9 Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN B P42 Y45 P39 Y42
BS02 M6P B Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y42 Q63 Y99 D100 N101 H102 R108 E130 R132 Y140
Gene Ontology
Molecular Function
GO:0019904 protein domain specific binding
Biological Process
GO:0006622 protein targeting to lysosome
Cellular Component
GO:0005768 endosome
GO:0005794 Golgi apparatus

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External links
PDB RCSB:2rl9, PDBe:2rl9, PDBj:2rl9
PDBsum2rl9
PubMed18272523
UniProtP11456|MPRD_BOVIN Cation-dependent mannose-6-phosphate receptor (Gene Name=M6PR)

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