Structure of PDB 2qr9 Chain B

Receptor sequence
>2qr9B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
3D structure
PDB2qr9 NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 D538 E542 I53 K57 L67 V71 E75 D230 E234
BS02 HZ3 B M343 L346 T347 E353 F404 M421 L428 H524 M38 L41 T42 E48 F99 M116 L123 H216
External links
PDB RCSB:2qr9, PDBe:2qr9, PDBj:2qr9
PDBsum2qr9
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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