Structure of PDB 2qpo Chain B

Receptor sequence
>2qpoB (length=150) Species: 2336 (Thermotoga maritima) [Search protein sequence]
SGKLTVITGPMYSGKTTELLSFVEIYKLGKKKVAVFKPVEAHVIERPEEM
RKYIEEDTRGVFIDEVQFFNPSLFEVVKDLLDRGIDVFCAGLDLTHKQNP
FETTALLLSLADTVIKKKAVCHRCGEYNATLTLKVEKYIAVCRDCYNTLK
3D structure
PDB2qpo Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.21: thymidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C140 C143 C176 C121 C124 C145
Gene Ontology
Molecular Function
GO:0004797 thymidine kinase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016301 kinase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process
GO:0016310 phosphorylation
GO:0046104 thymidine metabolic process
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2qpo, PDBe:2qpo, PDBj:2qpo
PDBsum2qpo
PubMed18073106
UniProtQ9WYN2|KITH_THEMA Thymidine kinase (Gene Name=tdk)

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