Structure of PDB 2qgw Chain B

Receptor sequence
>2qgwB (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB2qgw NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
ChainB
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 E380 D538 L539 E542 I54 K58 L68 E76 D231 L232 E235
BS02 EES B L346 T347 A350 E353 F404 H524 L525 L42 T43 A46 E49 F100 H217 L218
External links
PDB RCSB:2qgw, PDBe:2qgw, PDBj:2qgw
PDBsum2qgw
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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