Structure of PDB 2qe4 Chain B

Receptor sequence
>2qe4B (length=204) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSESMMGLLTNLADRELVHMINWAKRVP
GFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQG
KSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFEKDH
IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEH
LYSM
3D structure
PDB2qe4 Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JJ3 B M343 L346 A350 E353 F404 H524 L525 M28 L31 A35 E38 F89 H200 L201 MOAD: Ki=11nM
BindingDB: Ki=11nM
External links
PDB RCSB:2qe4, PDBe:2qe4, PDBj:2qe4
PDBsum2qe4
PubMed17662603
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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