Structure of PDB 2qb0 Chain B

Receptor sequence
>2qb0B (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
SIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLL
LTKEDFRYRSPHSGDVLYELLQHILKQAGPNIFEMLRIDEGLRLKIYKDT
EGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFCQDV
DAAVRGILRNAKLKPVYDSLDCVRRAALINMVFQMGETGVAGFTNSLRML
QQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYK
3D structure
PDB2qb0 Polymer-driven crystallization.
ChainB
Resolution2.56 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E104 D113
Catalytic site (residue number reindexed from 1) E90 D99
Enzyme Commision number 3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B H21 D33 D154 E157 H7 D19 D140 E143
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2qb0, PDBe:2qb0, PDBj:2qb0
PDBsum2qb0
PubMed17962407
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E)

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