Structure of PDB 2qab Chain B

Receptor sequence
>2qabB (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB2qab NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
ChainB
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 E380 D538 L539 E542 I54 K58 L68 E76 D234 L235 E238
BS02 EI1 B A350 E353 L387 F404 M421 H524 L525 A46 E49 L83 F100 M117 H220 L221
External links
PDB RCSB:2qab, PDBe:2qab, PDBj:2qab
PDBsum2qab
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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