Structure of PDB 2q9y Chain B

Receptor sequence
>2q9yB (length=352) Species: 5514 (Fusarium sporotrichioides) [Search protein sequence]
NFPTEYFLNTTVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQ
QQLLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDS
KDDPYPTMVNYFDDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIR
STLDFFEGCWIEQYNFGGFPGSHDYPQFLRRMNGLGHCVGASLWPKEQFN
ERSLFLEITSAIAQMENWMVWVNDLMSFYKEFDDERDQISLVKNYVVSDE
ISLHEALEKLTQDTLHSSKQMVAVFSDKDPQVMDTIECFMHGYVTWHLCD
RRYRLSEIYEKVKEEKTEDAQKFCKFYEQAANVGAVSPSEWAYPPVAQLA
NV
3D structure
PDB2q9y Exploring biosynthetic diversity with trichodiene synthase.
ChainB
Resolution2.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y93 T96 L97 D100 R182 K232 R304 Y305
Catalytic site (residue number reindexed from 1) Y91 T94 L95 D98 R180 K230 R302 Y303
Enzyme Commision number 4.2.3.6: trichodiene synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B N225 E233 N223 E231
BS02 POP B D100 R182 N225 S229 K232 E233 R304 Y305 D98 R180 N223 S227 K230 E231 R302 Y303
BS03 BTM B L97 R182 G186 L187 M221 Y295 W298 L95 R180 G184 L185 M219 Y293 W296 PDBbind-CN: -logKd/Ki=4.44,Ki=36uM
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016838 carbon-oxygen lyase activity, acting on phosphates
GO:0045482 trichodiene synthase activity
GO:0046872 metal ion binding
Biological Process
GO:0016106 sesquiterpenoid biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2q9y, PDBe:2q9y, PDBj:2q9y
PDBsum2q9y
PubMed17678871
UniProtP13513|TRI5_FUSSP Trichodiene synthase (Gene Name=TRI5)

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