Structure of PDB 2q9o Chain B

Receptor sequence

>2q9oB (length=559) Species: 204285 (Melanocarpus albomyces)

EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPD
GVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQK
DTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVV
GTIQINGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLI
NGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVI
AADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG
SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNS
FVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYP
VSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVP
AASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWL
FHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN
PYPKIDSGL

3D structure

• PDB: 2q9o A near atomic resolution structure of a Melanocarpus albomyces laccase.
• Chain: B
• Resolution: 1.3 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H93 H95 H138 H140 H431 H434 H436 H502 C503 H504 I505 H508 L513
• Catalytic site (residue number reindexed from 1): H93 H95 H138 H140 H431 H434 H436 H502 C503 H504 I505 H508 L513
• Enzyme Commision number: 1.10.3.2: laccase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CU	B	H431 C503 H508	H431 C503 H508
BS02	CU	B	H140 H436 H502	H140 H436 H502
BS03	CU	B	H95 H138 H504	H95 H138 H504
BS04	CU	B	H93 H434 H436	H93 H434 H436
BS05	OXY	B	H93 H138 H434 H502 H504	H93 H138 H434 H502 H504

Gene Ontology

Molecular Function

• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0052716 hydroquinone:oxygen oxidoreductase activity

Biological Process

• GO:0030245 cellulose catabolic process
• GO:0046274 lignin catabolic process

Cellular Component

• GO:0043245 extraorganismal space

External links

• PDB: RCSB:2q9o, PDBe:2q9o, PDBj:2q9o
• PDBsum: 2q9o
• PubMed: 18249560
• UniProt: Q70KY3|LAC1_MELAO Laccase-1 (Gene Name=LAC1)