Structure of PDB 2q6w Chain B

Receptor sequence
>2q6wB (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
TRPRFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTE
LGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVY
PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD
WTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRA
3D structure
PDB2q6w Crystallographic Structure of the Human Leukocyte Antigen DRA, DRB3*0101: Models of a Directional Alloimmune Response and Autoimmunity
ChainB
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R11 S13 Y26 V57 W61 L67 K71 R74 N77 Y78 H81 N82 V85 G86 R9 S11 Y24 V55 W59 L65 K69 R72 N75 Y76 H79 N80 V83 G84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2q6w, PDBe:2q6w, PDBj:2q6w
PDBsum2q6w
PubMed17583734
UniProtP79483|DRB3_HUMAN HLA class II histocompatibility antigen, DR beta 3 chain (Gene Name=HLA-DRB3)

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