Structure of PDB 2q11 Chain B |
>2q11B (length=388) Species: 9606 (Homo sapiens) [Search protein sequence] |
SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPQVTVRA NIAAITESDKFFIQGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVP NLFSLQLCGAGFPLQQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREW YYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKS IKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTQQSFR ITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDR ARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN |
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PDB | 2q11 2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead. |
Chain | B |
Resolution | 2.4 Å |
3D structure |
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