Structure of PDB 2q0g Chain B

Receptor sequence
>2q0gB (length=324) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
PSPAVVGRSLVNSFKQFVSKVDATYRLVLDCVAAVDPLMRLYTFGSTVVY
GVHEKGSDVDFVVLNKTDVEDGKGGDAATQVAKGLQADILAKLARVIRQK
HLSWNVEEVRRTRVPVVRVKGGGAVDFDITAYRRNGVRNSALLRAYFEQN
PPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNHLQFV
PPSTIDVSRVEPLPPHLPLEEPADEGLELGTQVLDFLHFFLHEFDSDKQV
ISLNRPGITTKEELDWTKSAEDFARMNGEKVHYQWCIEDPYELNLNVGRN
VTPLKRDFLRRHLEKARDTALLTI
3D structure
PDB2q0g Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D66 D68 D136 D58 D60 D128
BS02 UPU B F52 D68 V122 N147 Y189 F44 D60 V114 N139 Y181
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0050265 RNA uridylyltransferase activity
Biological Process
GO:0071076 RNA 3' uridylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0020023 kinetoplast

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Biological Process
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Cellular Component
External links
PDB RCSB:2q0g, PDBe:2q0g, PDBj:2q0g
PDBsum2q0g
PubMed17785418
UniProtQ381M1|TUT4_TRYB2 Terminal uridylyltransferase 4 (Gene Name=TUT4)

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