Structure of PDB 2pzl Chain B

Receptor sequence

>2pzlB (length=309) Species: 518 (Bordetella bronchiseptica) [Search protein sequence]

LVPRGSHMRILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPP
VAGLSVIEGSVTDAGLLERAFDSFKPTHVVHSAAAYKDPDDWAEDAATNV
QGSINVAKAASKAGVKRLLNFQTALCYGRPATVPIPIDSPTAPFTSYGIS
KTAGEAFLMMSDVPVVSLRLANVTGPRLAIGPIPTFYKRLKAGQKCFCSD
TVRDFLDMSDFLAIADLSLQEGRPTGVFNVSTGEGHSIKEVFDVVLDYVG
APVPVVAPGADDVPSVVLDPSKTETEFGWKAKVDFKDTITGQLAWYDKYG
VTDIFSHLS

3D structure

PDB

2pzl Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.

Chain

Resolution

2.39 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	T116 Y140 K144 P169
Catalytic site (residue number reindexed from 1)	T123 Y147 K151 P176
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	B	G7 G10 C11 L12 D31 N32 F33 T35 G36 S53 V54 S75 A76 A77 Y79 T91 F114 Q115 T116 Y140 K144 N165	G14 G17 C18 L19 D38 N39 F40 T42 G43 S60 V61 S82 A83 A84 Y86 T98 F121 Q122 T123 Y147 K151 N172
BS02	UDP	B	F179 F190 C191 S192 T194 I231 D259	F186 F197 C198 S199 T201 I238 D262

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0016740	transferase activity

	Biological Process
GO:0006541	glutamine metabolic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:2pzl, PDBe:2pzl, PDBj:2pzl
PDBsum	2pzl
PubMed	17950751
UniProt	O87988

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