Structure of PDB 2pw2 Chain B

Receptor sequence

>2pw2B (length=221) Species: 9606 (Homo sapiens) [Search protein sequence]

RITLKESGPPLVKPTQTLTLTCSFSGFSLSDFGVGVGWIRQPPGKALEWL
AIIYSDDDKRYSPSLNTRLTITKDTSKNQVVLVMTRVSPVDTATYFCAHR
RGPTTLFGVPIARGPVNAMDVWGQGITVTISSTSTKGPSVFPLAPTAALG
CLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSQ
TYTCNVNHKPSNTKVDKRVEP

3D structure

PDB

2pw2 Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.

Chain

Resolution

2.55 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	G33 Y52 D54 D56 R58 R95 P98 R100H V100K	G33 Y54 D56 D58 R60 R100 P103 R113 V116

External links

PDB	RCSB:2pw2, PDBe:2pw2, PDBj:2pw2
PDBsum	2pw2
PubMed	19740978

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