Structure of PDB 2pup Chain B

Receptor sequence
>2pupB (length=370) Species: 1423 (Bacillus subtilis) [Search protein sequence]
YETLNESSAVALAVKLGLTLTCQEIGDNYVFHIYDQERALIIKQAVPWPL
TIDRARIESSALIRQGEHVPHLVPRVFYSDTEMAVTVMEDLSHLKIARKG
LIEGENYPHLSQHIGEFLGKTLFYSSDYALEPKVKKQLVKQFTNPELCDI
TERLVFTDPFFDHDTNDFEEELRPFVEKLWNNDSVKIEAAKLKKSFLTSA
ETLIHGDLHTGSIFASEHETKVIDPEFAFYGPIGFDVGQFIANLFLNALS
RDGADREPLYEHVNQVWETFEETFSEAWQKDSLDVYANIDGYLTDTLSHI
FEEAIGFAGCELIRRTIGLAHVADLDTIVPFDKRIGRKRLALETGTAFIE
KRSEFKTITDVIELFKLLVK
3D structure
PDB2pup Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.100: S-methyl-5-thioribose kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D250 E252 D224 E226
BS02 ADP B N44 V46 I59 K61 M114 D116 L117 F240 D250 E252 N28 V30 I41 K43 M88 D90 L91 F214 D224 E226
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046522 S-methyl-5-thioribose kinase activity
Biological Process
GO:0009086 methionine biosynthetic process
GO:0016310 phosphorylation
GO:0019509 L-methionine salvage from methylthioadenosine

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Molecular Function
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Biological Process
External links
PDB RCSB:2pup, PDBe:2pup, PDBj:2pup
PDBsum2pup
PubMed17522047
UniProtO31663|MTNK_BACSU Methylthioribose kinase (Gene Name=mtnK)

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