Structure of PDB 2pon Chain B

Receptor sequence
>2ponB (length=156) Species: 9606 (Homo sapiens) [Search protein sequence]
MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEAVKQAL
REAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRI
VAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDT
FVELYG
3D structure
PDB2pon Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B E112 F113 Y117 F121 L124 Q127 L128 H129 S138 V142 E145 D149 N152 W153 G154 R155 F162 N201 T206 E209 L210 Y211 E56 F57 Y61 F65 L68 Q71 L72 H73 S82 V86 E89 D93 N96 W97 G98 R99 F106 N145 T150 E153 L154 Y155
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2pon, PDBe:2pon, PDBj:2pon
PDBsum2pon
PubMed17659302
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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