Structure of PDB 2po3 Chain B

Receptor sequence
>2po3B (length=392) Species: 54571 (Streptomyces venezuelae) [Search protein sequence]
ALSDLAFFGGPAAFDQPLLVGRPNRIDRARLYERLDRALDSQWLSNGGPL
VREFEERVAGLAGVRHAVATCNATAGLQLLAHAAGLTGEVIMPSMTFAAT
PHALRWIGLTPVFADIDPDTGNLDPDQVAAAVTPRTSAVVGVHLWGRPCA
ADQLRKVADEHGLRLYFDAAHALGCAVDGRPAGSLGDAEVFSFHATKAVN
AFEGGAVVTDDADLAARIRALHNFGFDLPGGSPAGGTNAKMSEAAAAMGL
TSLDAFPEVIDRNRRNHAAYREHLADLPGVLVADHDRHGLNNHQYVIVEI
DEATTGIHRDLVMEVLKAEGVHTRAYFSPGCHELEPYRGQPHAPLPHTER
LAARVLSLPTGTAIGDDDIRRVADLLRLCATRGRELTARHRD
3D structure
PDB2po3 Molecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine
ChainB
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F2100 D2171 H2174 H2197 K2200 G2233 K2243
Catalytic site (residue number reindexed from 1) F97 D168 H171 H194 K197 G230 K240
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T4K B Q2045 N2049 N2241 Q42 N46 N238
BS02 T4K B V2023 G2024 P2026 A2076 T2077 F2100 D2171 A2173 H2174 S2195 H2197 T2199 K2200 Y2329 V20 G21 P23 A73 T74 F97 D168 A170 H171 S192 H194 T196 K197 Y326
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0009058 biosynthetic process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2po3, PDBe:2po3, PDBj:2po3
PDBsum2po3
PubMed17630700
UniProtQ9ZGH0

[Back to BioLiP]