Structure of PDB 2pnq Chain B

Receptor sequence
>2pnqB (length=382) Species: 10116 (Rattus norvegicus) [Search protein sequence]
LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNRLPANAPIEDRRSA
TTCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENA
VELLPILQWHKHPNDYFSKEASKLYFNGLRTYWQELIDLDIDVKEALINA
FKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANT
GDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELQRLKLEHPKNEAKSVVK
QDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDPPNYHTPPYLTAEPE
VTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQQNAATH
LIRHAVGYRDDITIIVVQFNSHVVGAYQNQEQ
3D structure
PDB2pnq Crystal structure of pyruvate dehydrogenase phosphatase 1 and its functional implications.
ChainB
Resolution1.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.43: [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D73 G74 D65 G66
BS02 MG B D73 D347 D445 D65 D318 D360
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2pnq, PDBe:2pnq, PDBj:2pnq
PDBsum2pnq
PubMed17532339
UniProtO88483|PDP1_RAT [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (Gene Name=Pdp1)

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